Ventilated surgical and post-surgical recovery systems for rodent research

用于啮齿动物研究的通风手术和术后恢复系统

• 批准号: RTI-2018-00955
• 负责人: Mohajerani, Majid
• 金额: $ 10.93万
• 依托单位: University of Lethbridge
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=642173
• 关键词: Ventilated; surgical; post; recovery; systems

We are requesting new rodent surgical and post-surgical infrastructure to support our research and training activities in the Canadian Centre for Behavioural Neuroscience at the University of Lethbridge. The application is to support the acquisition of mobile ventilated surgical and dissection table together with recovery cabinet. The immediate need is prompted by the imminent move of the vivarium at the University of Lethbridge from its current location in the building housing the CCBN, a multidisciplinary research institute, into a new science building currently under construction, that will house not only CCBN but all natural science disciplines, scheduled to be opened summer 2019. At present, we have no individually ventilated systems to assist with rodent surgery, post-surgery recovery and perfusion/tissue collection processes. The new vivarium was designed and has been constructed in such a way that the surgical, post-surgical recovery and perfusion/tissue collection rooms will only accommodate individually ventilated units and the existing traditional non-mobile systems cannot be moved into the new building. Performing surgical procedures are essential to our NSERC-funded rodent-based research. There will be a significant interruption of our research projects along with the work of trainees if we fail to acquire the surgical systems and associated recovery cabinets. Apart from the requirement prompted by the move of the vivarium into a newly constructed building outlined in the proposal, the ventilated recovery cabinets are preferred by vivarium experts as they minimize the stress and circadian rhythm disturbance and provide individualized control over several environmental factors, such as temperature that will ultimately improve the scientific robustness of our discoveries. The acquisition of these critical items is central to our NSERC-funded

我们正在申请新的啮齿动物手术和手术后基础设施，以支持我们在莱斯布里奇大学加拿大行为神经科学中心的研究和培训活动。该应用程序用于支持移动的通风手术和解剖台以及恢复柜的获取。迫切的需求是由于莱斯布里奇大学的动物园即将从目前位于多学科研究机构CCBN的建筑中搬迁到目前正在建设的新科学大楼中，该大楼不仅将容纳CCBN，还将容纳所有自然科学学科，计划于2019年夏季开放。目前，我们没有单独的通风系统来协助啮齿动物手术、术后恢复和灌注/组织收集过程。新动物园的设计和建造方式是，手术室、术后恢复室和灌注/组织收集室只能容纳单独通风的单元，现有的传统非移动系统不能移入新建筑。执行外科手术是必不可少的，我们的NSERC资助的啮齿动物为基础的研究。如果我们不能获得手术系统和相关的恢复柜，我们的研究项目和受训人员的工作将沿着中断。除了将动物园搬到提案中概述的新建建筑物所提出的要求外，通风恢复柜是动物园专家的首选，因为它们最大限度地减少了压力和昼夜节律干扰，并提供了对几个环境因素的个性化控制，例如温度，这将最终提高我们发现的科学稳健性。这些关键项目的收购是我们的NSERC资助的核心