Environmental Physiology and Toxicology

环境生理学和毒理学

• 批准号: 1000228131-2011
• 负责人: Vijayan, Mathilakath
• 金额: $ 14.57万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=643196
• 关键词: Environmental; Physiology; Toxicology

My research program intends to address how growth, stress and reproductive performances of fish are impacted by environmental contaminants. The over-arching goal is to enhance our fundamental knowledge about the stress coping mechanisms in fish to develop novel risk assessment tools for predicting population-level damage by contaminants. A major focus will be on maternal transfer of contaminants to eggs and its implication on growth, development and stress performances. The applied aspect of this research program will be in the development of gene, protein and/or metabolite probe as biosensors of fish performance to predict long-term and multi-generational impacts of contaminants for risk assessment.

我的研究项目旨在解决环境污染物如何影响鱼类的生长、压力和繁殖性能。总体目标是增强我们的 有关鱼类应激应对机制的基础知识，以开发新的风险 用于预测污染物对人口造成的损害的评估工具。主要关注点是母体污染物向鸡蛋的转移及其对生长、发育和应激表现的影响。该研究计划的应用方面将是开发基因、蛋白质和/或代谢物探针作为鱼类性能的生物传感器，以预测污染物的长期和多代影响，以进行风险评估。