Environmental Physiology and Toxicology
Environmental Physiology and Toxicology
批准号:
CRC-2018-00233
负责人:
Vijayan, Mathilakath
金额:
$10.93万
依托单位:
依托单位国家:
加拿大
项目类别:
Canada Research Chairs
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-01-01 至 2020-12-31
中文摘要
我的研究旨在揭示动物应对压力的分子机制。具体地说,我的研究重点是糖皮质激素信号,这是一种保守的压力应对途径,对动物生长和福利的各个方面都是必不可少的。我们对斑马鱼进行了基因编辑,通过删除与压力相关的基因来阐明与压力应对有关的机制。这些基因敲除模型将使我们能够识别针对应力轴的新污染物,并降低动物的适应性。我的实验室还将确定导致长期和多代影响压力和生长表现的机制,以应对发育过程中暴露于环境污染物。
英文摘要
My research aims to uncover the molecular mechanisms that allow animals to cope with stress. Specifically, my research will focus on glucocorticoid signalling, a conserved stress coping pathway, which is essential for all aspects of animal growth and welfare. We have genetically edited zebrafish to elucidate the mechanisms involved in stress coping by deleting stress-related genes. These knockout models will allow us to identify emerging contaminants targeting the stress axis and reducing animal fitness. My lab will also determine the mechanisms leading to long-term and multigenerational impacts on stress and growth performances in response to developmental exposure to environmental contaminants.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Role of glucocorticoid signalling in stress adaptation
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批准号:RGPIN-2019-06291
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项目类别:Discovery Grants Program - Individual
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资助金额:$6.99万
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财政年份:2022
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负责人:Vijayan, Mathilakath
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依托单位:
Environmental Physiology and Toxicology
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批准号:CRC-2018-00233
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项目类别:Canada Research Chairs
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资助金额:$14.57万
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财政年份:2022
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负责人:Vijayan, Mathilakath
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依托单位:
Role of glucocorticoid signalling in stress adaptation
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批准号:RGPIN-2019-06291
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项目类别:Discovery Grants Program - Individual
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资助金额:$6.99万
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财政年份:2021
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负责人:Vijayan, Mathilakath
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依托单位:
Total suspended solids impact on native fish species in the Bow River
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批准号:558259-2020
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项目类别:Alliance Grants
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资助金额:$6.23万
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财政年份:2021
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负责人:Vijayan, Mathilakath
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依托单位:
Environmental Physiology And Toxicology
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批准号:CRC-2018-00233
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项目类别:Canada Research Chairs
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资助金额:$14.57万
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财政年份:2021
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负责人:Vijayan, Mathilakath
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依托单位:
Environmental Physiology and Toxicology
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批准号:CRC-2018-00233
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项目类别:Canada Research Chairs
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资助金额:$14.57万
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财政年份:2020
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负责人:Vijayan, Mathilakath
-
依托单位:
Total suspended solids impact on native fish species in the Bow River
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批准号:558259-2020
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项目类别:Alliance Grants
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资助金额:$6.67万
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财政年份:2020
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负责人:Vijayan, Mathilakath
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依托单位:
Role of glucocorticoid signalling in stress adaptation
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批准号:RGPIN-2019-06291
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项目类别:Discovery Grants Program - Individual
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资助金额:$6.99万
-
财政年份:2020
-
负责人:Vijayan, Mathilakath
-
依托单位:
Role of glucocorticoid signalling in stress adaptation
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批准号:RGPIN-2019-06291
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项目类别:Discovery Grants Program - Individual
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资助金额:$6.99万
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财政年份:2019
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负责人:Vijayan, Mathilakath
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依托单位:
State-of-the-art biological nanoparticle tracking instrument for interdisciplinary use
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批准号:RTI-2020-00372
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项目类别:Research Tools and Instruments
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资助金额:$10.91万
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财政年份:2019
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负责人:Vijayan, Mathilakath
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依托单位:
Environmental Physiology and Toxicology
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批准号:1000228131-2011
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项目类别:Canada Research Chairs
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资助金额:$3.64万
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财政年份:2019
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负责人:Vijayan, Mathilakath
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依托单位:
Environmental Physiology and Toxicology
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批准号:1000228131-2011
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项目类别:Canada Research Chairs
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资助金额:$14.57万
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财政年份:2018
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负责人:Vijayan, Mathilakath
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依托单位:
Cortisol stress axis development and function in fish
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批准号:217481-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.42万
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财政年份:2018
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负责人:Vijayan, Mathilakath
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依托单位:
Municipal waste water effluent impact on native fish: mechanisms of action and BIOMIC signatures
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批准号:463163-2014
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项目类别:Strategic Projects - Group
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资助金额:$13.95万
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财政年份:2017
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负责人:Vijayan, Mathilakath
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依托单位:
Environmental Physiology and Toxicology
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批准号:1000228131-2011
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项目类别:Canada Research Chairs
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资助金额:$14.57万
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财政年份:2017
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负责人:Vijayan, Mathilakath
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依托单位:
Cortisol stress axis development and function in fish
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批准号:217481-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.42万
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财政年份:2017
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负责人:Vijayan, Mathilakath
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依托单位:
Environmental Physiology and Toxicology
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批准号:1000228131-2011
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项目类别:Canada Research Chairs
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资助金额:$14.57万
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财政年份:2016
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负责人:Vijayan, Mathilakath
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依托单位:
Cortisol stress axis development and function in fish
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批准号:217481-2013
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.42万
-
财政年份:2016
-
负责人:Vijayan, Mathilakath
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依托单位:
Municipal waste water effluent impact on native fish: mechanisms of action and BIOMIC signatures
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批准号:463163-2014
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项目类别:Strategic Projects - Group
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资助金额:$13.66万
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财政年份:2015
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负责人:Vijayan, Mathilakath
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依托单位:
Environmental Physiology and Toxicology
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批准号:1228131-2011
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项目类别:Canada Research Chairs
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资助金额:$14.57万
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财政年份:2015
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负责人:Vijayan, Mathilakath
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依托单位:
海外基金