Anti-bacterial effect of neem oil and karanja oil delivered by Actigate technology against phytopathogenic bacteria******

Terramera Inc.是一家清洁技术公司，正在开发传统化学农药和化肥的高性能可持续替代品。Terramera创造了健康、安全的环境和不含有毒化学物质的作物，并使可持续和有机农业变得更便宜、更多产和丰富。Terramera致力于提供最好的可持续产品和解决方案，以改善健康和生活质量，并被信任保护人、植物、财产和我们的地球。**马铃薯是加拿大最重要的蔬菜作物，占2014年蔬菜总面积的59%。影响马铃薯生产的病害有很多，但最具挑战性的病害之一是由链霉菌引起的马铃薯赤霉病。块茎腐烂病的特征是在马铃薯块茎表面形成浅层、隆起或凹陷的病斑，这些病斑对受影响的块茎作物的品质和市场价值产生了负面影响。管理CS的传统控制策略效率低下且经常失败，有些策略可能会对环境产生负面影响。**本项目的目的是调查Terramera公司开发的天然植物制剂是否可以用来控制导致CS病的细菌病原体。不同的配方将被测试它们杀死或抑制细菌生长的能力，以及它们抑制导致CS的关键毒力因子的产生的能力。显示最佳活性的配方随后将在CS生物测定模型中进行测试，以确定它们是否可以抑制病原体引起的疾病症状的发展。预计拟议的工作将促进Terramera公司开发天然产品，今后可将其作为控制CS病的管理战略的一部分，从而减少该病对加拿大马铃薯生产行业的经济影响。

Terramera Inc. is a clean-tech company developing high-performance sustainable alternatives to conventional chemical pesticides and fertilizers. Terramera creates healthy, safe environments and crops free of toxic chemicals, and makes sustainable and organic farming cheaper, more productive and abundant. Terramera is committed to providing the best sustainable products and solutions that improve health and quality of life, and are trusted to protect people, plants, property and our earth.** Potato is the most important vegetable crop in Canada, accounting for 59% of the total vegetable acreage in 2014. A number of diseases can affect potato production, but one of the most challenging diseases to control is potato common scab (CS) disease, which is caused by Streptomyces bacteria. CS is characterized by the formation of superficial, raised or pitted lesions on the surface of potato tubers, and these lesions negatively impact the quality and market value of the affected tuber crop. Traditional control strategies for managing CS are inefficient and often fail, and some can have negative impacts on the environment.** The aim of this project is to investigate whether natural plant-based formulations developed by Terramera can be used to control the bacterial pathogens responsible for CS disease. Different formulations will be tested for their ability to kill or inhibit the growth of the bacteria as well as for their ability to inhibit the production of the key virulence factor responsible for CS. Formulations showing the best activity will then be tested in a CS bioassay model to determine if they can suppress the development of disease symptoms by the pathogens. It is anticipated that the proposed work will facilitate the development of natural products by Terramera that in the future could be applied as part of a management strategy for controlling CS disease, thereby reducing the economic impact of the disease on the potato production industry in Canada.******