Fouling removal and system optimization of cleaning in place systems

总部位于安大略省安卡斯特市的麦克弗森公司是一家设计、制造和工程服务提供商，致力于原地清洁(CIP)和原地灭菌(SIP)系统，用于对制药和食品加工行业的设备进行清洁和消毒。清洗或杀菌是通过将来自CIP或SIP装置的清洗液通过生产线中的**组件来执行的。McFusion计划扩大他们的市场，特别是在食品和饮料行业。**扩展到不同的行业和流程将需要使用**更短的设计周期来定制和优化CIP和SIP系统。为了实现这一目标，麦克弗森已与麦克马斯特大学展开合作，为他们的CIP和SIP系统开发系统**分析工具。McFlusion和麦克马斯特大学的这项初步合作的总体目标是：(I)开发一种系统分析工具，该工具可以预测不同**生产线的CIP和SIP系统的性能，以及(Ii)检查污垢层清除率。建议使用OCE和NSERC的资金来**实现这两个目标。基于现有的关联式、经验数据和分析模型，将建立典型生产线中不同**组分的流动和热工性能以及污垢清除的模型。组件的分析**模块将与CIP或SIP单元的模型以及高级控制器的模型结合到**系统分析工具中，麦克福里森可以使用该工具来预测不同生产线上的CIP单元的性能。

McFlusion Corporation, based in Ancaster Ontario, is a designer, manufacturer and engineering service provider for cleaning in**place (CIP) and sterilization in place (SIP) systems used to clean and sterilize equipment in the pharmaceutical and food**processing industries. Cleaning or sterilization is performed by passing the cleaning fluid from CIP or SIP units through the**components in the processing lines. McFlusion has plans to expand their markets, especially in the food and beverage industries.**Expansion into different industries and processes would require customizing and optimizing the CIP and SIP systems using much**shorter design cycle times. To achieve this, McFlusion has initiated a collaboration with McMaster University to develop system**analysis tools for their CIP and SIP systems. The overall objectives of this initial collaboration between McFlusion and McMaster**University are: (i) To develop a system analysis tool that can predict the performance of CIP and SIP systems for different**processing lines and (ii) To examine the fouling layer removal rates. It is proposed to use funding from OCE and NSERC to**achieve the two objectives. Models will be developed for the flow and thermal performance and fouling removal in the different**components in typical processing lines based on existing correlations, empirical data, and analytical models. The analysis**modules for the components will be incorporated with models for the CIP or SIP units and for the advanced controller into a**systems analysis tool that can be used by McFluison to predict the performance of CIP units for different processing lines.