Microinstrumentation featuring flexible polymers: from discrete devices to full electronic and microfluidic systems

采用柔性聚合物的显微仪器：从分立器件到完整的电子和微流体系统

• 批准号: RGPIN-2014-05552
• 负责人: Gray, Bonnie
• 金额: $ 2.7万
• 依托单位: Simon Fraser University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=652365
• 关键词: Microinstrumentation; featuring; flexible; polymers; discrete

My research program focuses on the development of innovative microfabrication and enabling technologies for next generation microsensors, microfluidic systems, and microelectromechanical systems (MEMS). Through the Discovery Grant program, my lab (Microinstrumentation Lab, uiL) has pioneered essential enabling technologies through a concentrated and systematic approach. These enabling technologies have included advanced microfluidic flow control; development of micropatterned functional electronic and magnetic composite polymers (CPs); technologies to aid in integrated, chip-to-chip and chip-to-world microfluidic interconnect; and flexible microfluidic and wearable textile-based biosensor device-level technologies. **The long-term goals of my research are to establish a comprehensive library of interconnects and microfluidic, microsensor, electronic, and optical components with well-defined functionality and interface requirements to facilitate development of new microfluidic instruments. I plan to integrate CPs into microfluidic systems on rigid and flexible substrates, including commercial microfluidic polymers and textiles, to achieve innovative system performance enabled by these functional materials. The applications of this research will be the creation of "technically fun and socially relevant" microfluidic instrumentation for applications including but not limited to: health care, athletic performance, hazardous environment exposure, immunology, food packaging, biological cell studies, and disease diagnostics. HQP trained during the duration of the program will become Canada's next generation of technological leaders in these sectors.**Over the next five years, the proposed research program will focus on the following objectives:*1. Development of a combined microfluidic and electronic framework (MEF), including power sources and devices with C-CP/M-CP structures, on flexible polymer and textile platforms.*2. Establishment of a library of system-level engineering building blocks of platforms, interconnects, and device packaging to facilitate systematic microinstrument development.*3. Development of methods to combine M-CPs with microfluidic thermoplastic polymers (TPs) to provide new microfluidic actuation mechanisms for these industrially-relevant material platforms.*4. Demonstration of the MEF for combining example devices relevant to wearable monitoring.**New and exciting research into wearable electronics, functional nanocomposite polymers, flexible microfluidics, and commercial polymer microfluidics is reported on a daily basis. However, much of this research is specific to each field, despite the enormous potential that the convergence of these research areas has for the future of health care, worker safety, food safety, consumer devices, and commercial microfluidics. The proposed research program offers a new and innovative approach of powerful, general-purpose frameworks to systematically interface CP-based, microfluidic, and electronic devices simultaneously on flexible polymer, textile, or industrial polymer platforms. Such an approach offers practical solutions for industry in areas such as worker safety; UV-index, heart, and lactose monitoring for athletic clothing; and glucose monitoring. The integration of rare-earth M-CP actuators with commercial microfluidics will be pioneering, offering high-deflection, low-power actuators for increased portability. The strength of the proposed research program is its ability to provide technological frameworks to develop not just one instrument, but to provide essential, enabling technologies for on-going development of new wearable and portable microfluidics, placing Canada at the forefront of sustainable development in these areas.

我的研究计划侧重于开发创新的微制造和下一代微传感器，微流体系统和微机电系统（MEMS）的使能技术。通过发现资助计划，我的实验室（微仪器实验室，uiL）通过集中和系统的方法开创了必要的使能技术。这些使能技术包括先进的微流体流动控制;微图案化功能性电子和磁性复合聚合物（CP）的开发;有助于集成的芯片到芯片和芯片到世界微流体互连的技术;以及灵活的微流体和基于可穿戴纺织品的生物传感器设备级技术。** 我的研究的长期目标是建立一个全面的互连和微流体，微传感器，电子和光学元件库，具有明确的功能和接口要求，以促进新的微流体仪器的开发。我计划将CP集成到刚性和柔性基底上的微流体系统中，包括商业微流体聚合物和纺织品，以实现这些功能材料所实现的创新系统性能。这项研究的应用将是创建“技术上有趣和社会相关”的微流体仪器，其应用包括但不限于：医疗保健，运动性能，危险环境暴露，免疫学，食品包装，生物细胞研究和疾病诊断。在该计划期间接受培训的HQP将成为加拿大这些领域的下一代技术领导者。在今后5年内，本研究计划将围绕以下目标展开：*1.在柔性聚合物和纺织品平台上开发组合微流体和电子框架（MEF），包括具有C-CP/M-CP结构的电源和设备。2.建立平台、互连和器件封装的系统级工程构建模块库，以促进系统化微仪器开发。3.开发将联合收割机M-CP与微流体热塑性聚合物（TP）结合的方法，为这些工业相关材料平台提供新的微流体驱动机制。* 4. MEF演示，用于结合与可穿戴监测相关的示例设备。**可穿戴电子产品、功能纳米复合聚合物、柔性微流体和商业聚合物微流体的新的令人兴奋的研究每天都有报道。然而，尽管这些研究领域的融合对医疗保健、工人安全、食品安全、消费设备和商业微流体的未来具有巨大的潜力，但这些研究中的大部分都是针对每个领域的。拟议的研究计划提供了一种强大的通用框架的新的创新方法，可以在柔性聚合物，纺织品或工业聚合物平台上同时系统地连接基于CP的微流体和电子设备。这种方法为工业领域提供了实用的解决方案，例如工人安全;运动服的紫外线指数，心脏和乳糖监测;以及葡萄糖监测。稀土M-CP致动器与商业微流体的集成将是开创性的，提供高偏转，低功率致动器，以提高便携性。拟议的研究计划的优势在于它能够提供技术框架，不仅开发一种仪器，而且为新的可穿戴和便携式微流体的持续发展提供必要的技术，使加拿大处于这些领域可持续发展的最前沿。