Microfluidic bioreactors for perfusion of 3D bioprinted tissues

点击翻译按钮获取中文摘要

3D printing has changed the ways of practice in many applications including biomedical and tissue engineering. In particular, 3D printing is now used for the bioprinting of vascular tissues and drug delivery. The existing 3D bioprinters suffer from a mimetic delivery system, known as perfusion system, to provide nutrients to cell-laden bioprinted hydrogels. In partnership with one of the pioneering companies in 3D bioprinting, this research aims at developing a microfluidic based perfusion system for the delivery of nutrients, oxygen and drugs to 3D tissues. These perfusion systems will benefit 3D printing industry in drastically expanding the capability for long-term cell culture, disease modeling and drug testing on vascular tissues. The industry partner for this project, Aspect Biosystems, is a leading tech company providing solutions for bioprinting. These perfusion systems will benefit Aspect Biosystems in drastically expanding their capability for long-term cell culture, disease modeling and drug testing on vascular tissues. The advancement in the perfusion system will open up new markets and will improve company competitiveness.****