PD-L1 modulation of the type I interferon response and its implications for the immune response against cancer and pathogens.
PD-L1 modulation of the type I interferon response and its implications for the immune response against cancer and pathogens.
批准号:
404152
负责人:
Hodgins Jonathan
金额:
$7.65万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-10-01 至 2021-10-01
中文摘要
PD-L1是一种能够抑制免疫系统的蛋白质。这种免疫抑制是当它与其他蛋白质结合时引起的,例如PD-1,PD-1在癌症中已经得到很好的表征(并且目前被FDA批准的多种治疗靶向用于治疗癌症)。
英文摘要
PD-L1 is a protein with the ability to dampen the immune system. This immune inhibition is caused when it binds to other proteins, such as PD-1, which has been well characterized in cancer (and is currently targeted by multiple FDA-approved therapies for
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