Development of raman biomarkers of oral health****

口腔健康拉曼生物标志物的开发****

• 批准号: 537551-2018
• 负责人: Murugkar, Sangeeta
• 金额: $ 1.82万
• 依托单位: Carleton University
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=660502
• 关键词: Development; raman; biomarkers; oral; health

WinTerra Global Technologies (WinTerra) is focused on improving the dental examination experience for both the practitioner and the patient by offering new tools that improve productivity and resource usage for the practice and reduce the negativity of the experience for the patient. To this goal, WinTerra is developing new dental probing technology to enhance the diagnostic capabilities of the periodontal exam. Current technology can only report pocket depth which does not closely correlate with pocket health. By adding better correlates of pocket health (like inflammation) one could initiate earlier treatment and provide better outcomes for patients. ** **Gingival crevicular fluid (GCF) is a real time source of fluids in human gum that is well correlated with blood composition, including inflammation markers, at any point in time. This project will be a collaboration between WinTerra and Carleton that will explore means of detection important biomarkers of health in the CGF using advanced photonic technologies to improve oral health assessment. **

WinTerra Global Technologies（WinTerra）致力于通过提供新的工具来改善从业者和患者的牙科检查体验，这些工具可以提高实践的生产力和资源使用率，并减少患者体验的负面影响。为了实现这一目标，WinTerra正在开发新的牙科探测技术，以提高牙周检查的诊断能力。目前的技术只能报告与牙周健康没有密切关系的牙周袋深度。通过增加口袋健康（如炎症）的更好的相关性，可以启动早期治疗，并为患者提供更好的结果。* 龈沟液（GCF）是人类牙龈中液体的真实的时间来源，在任何时间点与血液成分（包括炎症标志物）密切相关。该项目将是WinTerra和Carleton之间的合作，将探索使用先进的光子技术检测CGF中重要的健康生物标志物的方法，以改善口腔健康评估。**