Melatonin, sleep and circadian gene methylation, with implications for breast cancer risk among female shift workers

褪黑激素、睡眠和昼夜节律基因甲基化对女性轮班工人乳腺癌风险的影响

• 批准号: 406393
• 负责人: Felske Lindey
• 金额: $ 1.27万
• 依托单位: Queen's University (Kingston, Ontario)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-12-01 至 2019-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=406393&lang=en
• 关键词: Breast Cancer; Circadian Genes; Cross-Sectional Study; Environmental Risk Factors; Gene Methylation; Health Care Workers; Melatonin; Shift Work; Sleep

Breast cancer is the leading cause of cancer in Canadian women. Strong evidence has linked long-term shiftwork to breast cancer, but there remains uncertainty regarding the underlying mechanisms. In the healthcare industry, where shiftwork is necessary an

乳腺癌是加拿大妇女癌症的主要原因。强有力的证据表明，长期轮班工作与乳腺癌有关，但其潜在机制仍存在不确定性。在医疗保健行业，轮班工作是必要的，