Interactions Between Human ADAR1 and PACT and their Pro-viral Role in the Pathology of Human Immunodeficiency Virus
Interactions Between Human ADAR1 and PACT and their Pro-viral Role in the Pathology of Human Immunodeficiency Virus
批准号:
406435
负责人:
Dunkley Owen
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-12-01 至 2019-12-01
中文摘要
人类免疫缺陷病毒(HIV)进入细胞后,通过先天免疫受到限制,部分由细胞因子(包括干扰素(IFN))介导。与大多数人IFN刺激基因(ISG)的抗病毒作用相反,
英文摘要
Upon its entry in the cell, the Human Immunodeficiency Virus (HIV) is restricted through innate immunity, mediated in part by cytokines, including interferons (IFN). Contrary to the antiviral roles of most human IFN Stimulated Genes (ISGs), a discrete num
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