Molecular Mechanisms of Opening and Closing in Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channels

超极化激活的环核苷酸门控 (HCN) 通道打开和关闭的分子机制

• 批准号: 417488
• 负责人: Yip Delbert C
• 金额: $ 1.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-12-01 至 2019-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=417488&lang=en
• 关键词: Arrhythmia; Biophysics; Electrophysiology; Epilepsy; Gating; Hcn Channel; Hcn Mutations; Ion Channel Kinetics; Mathematical Modelling; Pacemaker Channel

Ion channels are proteins that act as microscopic conduits of electricity within our cells. Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) channels are a family of ion channels that control important biological functions such as heart rhythm an

离子通道是一种蛋白质，在我们的细胞内充当微观的电流管道。超极化激活的环核苷酸门控（HCN）通道是一类控制重要生物功能的离子通道，如心脏节律和呼吸功能。