Personalized nutrition

背景和问题。全基因组关联研究（GWAS）先前已经报道了许多称为单核苷酸多态性（SNP）的遗传变异与对omega-3脂肪酸的代谢反应相关。然而，关于这些SNP作为血浆甘油三酯水平降低的预测生物标志物的潜在作用知之甚少。目标.创建一个基因小组，以便设计一种创新且改进的DNA测试，用于对欧米茄-3脂肪酸的代谢反应。* 相关性。确定与血浆甘油三酯对omega-3脂肪酸补充剂的反应相关的遗传生物标志物，可供对营养遗传学检测感兴趣的工业合作伙伴使用。该SNP小组的建立将导致工业合作伙伴改进基于DNA的营养基因组测试。 ************

Background and Problem. A number of genetic variants called single nucleotide polymorphisms (SNPs) have been previously reported by genome-wide association studies (GWAS) to be associated with the metabolic response to omega-3 fatty acids. However, little is known about the potential role of these SNPs as predictive biomarkers of the decrease in plasma triglyceride levels.****Objectives. To create a genetic panel allowing to the design of an innovative and improved DNA test for the metabolic response to omega-3 fatty acids. ****Relevance. To identify genetic biomarkers associated with the plasma triglyceride response to an omega-3 fatty acid supplementation that can be used by an industrial partner interested in nutrigenetic testing. The setting-up of this panel of SNPs will lead to the improvement of a DNA-based nutrigenomic test by the industrial partner partner. ************