Delineating the role of the TRPM2 surveillance receptor in Rett syndrome
Delineating the role of the TRPM2 surveillance receptor in Rett syndrome
批准号:
400964
负责人:
Eubanks James H
金额:
$70.5万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-03-01 至 2024-03-01
中文摘要
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英文摘要
Rett syndrome is a devastating neurodevelopmental disorder affecting mostly girls. Spontaneous mutations within the X-linked MECP2 gene are the largest cause, but how deficiencies in MeCP2 protein function facilitate Rett syndrome pathogenesis remains la
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