Elucidating early bone alterations following acute rupture of the anterior cruciate ligament contributing to the development of post-traumatic osteoarthritis

阐明前十字韧带急性断裂后导致创伤后骨关节炎发展的早期骨改变

• 批准号: 411501
• 负责人: Knowles Nikolas K
• 金额: $ 10.2万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-09-01 至 2021-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=411501&lang=en
• 关键词: Anterior Cruciate Ligament (Acl); Bone Adaptation; Finite Element Modeling; Functional Loss; Imaging Biomarkers; Longitudinal Cohort; Multi-Modality Imaging; Osteoarthritis; Pain; X-Ray Computed Tomography

Medical imaging provides an important tool in diagnosing osteoarthritis (OA) characteristics; however, early joint alterations that may contribute to OA progression and the relationship to pain and loss of function are difficult to capture due to the lack

医学成像提供了诊断骨关节炎（OA）特征的重要工具;然而，由于缺乏影像学检查，很难捕获可能导致OA进展的早期关节改变以及与疼痛和功能丧失的关系。