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Understanding the mechanism of vascular elastocalcinosis and its prevention by MGP

Understanding the mechanism of vascular elastocalcinosis and its prevention by MGP
了解血管弹力钙质沉着症的机制及其 MGP 的预防
批准号:
409272
负责人:
Murshed Monzur
金额:
$67.43万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2024-09-01

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中文摘要
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英文摘要
Abnormal mineral deposition in the vascular tissues (vascular calcification) is a life-threatening condition that is associated with both genetic and metabolic disorders. Animal models are providing valuable information about the mechanisms of this proces
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Understanding how a novel mutation in matrix Gla protein causes skeletal anomalies
Understanding the pathophysiology of Keutel Syndrome: A path towards cure
  • 批准号:
    406805
  • 项目类别:
    Operating Grants
  • 资助金额:
    $8.38万
  • 财政年份:
    2019
  • 负责人:
    Murshed Monzur
  • 依托单位:
Midface hypoplasia caused by cartilage calcification: A mechanistic study with translational implications
Molecular mechanisms underlying the vascular calcification phenotype in matrix gla protein-deficient mice
  • 批准号:
    255106
  • 项目类别:
    Operating Grants
  • 资助金额:
    $21.14万
  • 财政年份:
    2012
  • 负责人:
    Murshed Monzur
  • 依托单位:
海外基金