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Molecular mechanisms underlying the vascular calcification phenotype in matrix gla protein-deficient mice

Molecular mechanisms underlying the vascular calcification phenotype in matrix gla protein-deficient mice
基质gla蛋白缺陷小鼠血管钙化表型的分子机制
批准号：
255106
负责人：
Murshed Monzur
金额：
$21.14万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-03-01 至 2015-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=255106&lang=en
关键词：
Arteriovenous Malformation Blood Vessels Bone Mineralization Ectopic Calcification Elastin Extracellular Matrix Genetics Matrix Degrading Enzymes Matrix Gla Protein Transgenic And Knockout Models

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英文摘要
Lay Summary: Abnormal mineral deposition in the soft tissues (calcification) can be seen in some life-threatening diseases. Mineral accumulation in the blood vessels is a common example of soft tissue calcification. Vascular calcification can be seen in d
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Understanding how a novel mutation in matrix Gla protein causes skeletal anomalies
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  • 批准号：
    406805
  • 项目类别：
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  • 资助金额：
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  • 财政年份：
    2019
  • 负责人：
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  • 依托单位：
    McGill University
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