Understanding the basis of diaphragmatic weakness in critical illness

了解危重疾病中膈肌无力的基础

• 批准号: 407809
• 负责人: Petrof Basil J
• 金额: $ 52.94万
• 依托单位: Research Institute of the McGill University Health Centre
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-09-01 至 2024-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=407809&lang=en
• 关键词: Critical Illness Myopathy; Cytokines; Diaphragm Function; Mechanical Ventilation; Mitochondria; Muscle Atrophy; Muscle Injury; Muscle Physiology; Muscle Regeneration; Sepsis

Patients admitted to the intensive care unit (ICU) often develop a severe loss of muscularity and muscle weakness, which can also involve the main breathing muscle (the diaphragm). This causes difficulties in removing patients from artificial breathing ma

进入重症监护室（ICU）的患者通常会出现严重的肌肉萎缩和肌肉无力，这也可能涉及主要的呼吸肌（膈肌）。这就造成了将病人从人工呼吸机中移出的困难。