Multisensory integration during self-motion perception

自我运动感知过程中的多感官整合

• 批准号: RGPIN-2015-06619
• 负责人: Campos, Jennifer
• 金额: $ 1.75万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=679870
• 关键词: Multisensory; integration; during; self; motion

Overview: As we move through complex environments, our brain must effectively integrate information from vision, muscles and joints (proprioception), and the acceleration detectors in the inner ear (vestibular). An optimal integration of these sensory and motor inputs allows us to estimate movement parameters such as speed, distance, and heading direction with greater certainty. Traditionally, each of these sensory systems has been studied independently of one another, but this research program is aimed at quantifying how these multiple sensory inputs are integrated in the brain during self-motion. The objectives of the proposed research program will be to empirically evaluate established tenets of multisensory integration, as well as to introduce novel experimental manipulations aimed at better characterizing visual, proprioceptive, and vestibular integration during self-motion perception. Specifically it aims to:***Objective 1: In the context of self-motion perception, identify the limits of the multisensory "binding window" (i.e. the range of spatio-temporal disparities over which multiple cues are still integrated), by measuring how the magnitude of a) spatial and b) temporal conflicts between visual and vestibular signals affect optimal cue weighting.***Objective 2: Assess the effects of changing cue reliabilities (e.g. reducing the quality of dynamic visual input) on multisensory self-motion perception during either experimentally introduced a) transient reductions in individual cue reliabilities, or b) prolonged reductions in individual cue reliabilities.***Objective 3: Consider the aging brain as a model for understanding how naturally-occurring, global reductions in cue reliabilities across several sensory systems (e.g. loss of visual acuity and vestibular sensitivity) affect multisensory integration strategies. ***Scientific Approach: This research will be conducted using a state-of-the-art, immersive, Virtual Reality lab combined with a motion platform. These facilities allow us to systematically manipulate the information provided to each sensory channel, as well as to create subtle conflicts between sensory systems. We will use well-established psychophysical paradigms during both passive self-motion tasks (i.e. heading estimation on the motion simulator) and active self-motion tasks (i.e. travelled distance estimation while walking on a treadmill).****Impact: These studies will have significant, global theoretical impacts in the fields of multisensory integration. They will make particularly relevant contributions to the literatures on self-motion perception, spatial updating, locomotion, and aging. Long-term applied impacts of these studies may also be observed in fields including, locomotor rehabilitation, design of simulators, and vehicle design for an aging population.

概述：当我们在复杂的环境中移动时，我们的大脑必须有效地整合来自视觉、肌肉和关节（本体感觉）以及内耳（前庭）中的加速度检测器的信息。这些感觉和运动输入的最佳整合使我们能够更确定地估计运动参数，如速度，距离和航向。传统上，这些感觉系统中的每一个都是独立研究的，但这项研究计划的目的是量化这些多个感觉输入在自我运动过程中如何整合到大脑中。拟议的研究计划的目标将是经验性地评估既定的多感觉整合的原则，以及引入新的实验操作，旨在更好地表征视觉，本体感受和前庭整合在自我运动感知。具体来说，它的目标是：* 目标1：在自我运动知觉的背景下，通过测量视觉和前庭信号之间的a）空间和B）时间冲突的大小如何影响最佳提示权重，确定多感觉“绑定窗口”（即多个提示仍然整合的时空差异范围）的限制。目标二：在实验引入的a）个体提示可靠性的短暂降低或B）个体提示可靠性的长期降低期间，评估改变提示可靠性（例如，降低动态视觉输入的质量）对多感官自我运动知觉的影响。*目标三：考虑老化的大脑作为一个模型，了解如何自然发生的，在几个感官系统的线索可靠性（如视觉敏锐度和前庭敏感性的损失）的整体降低影响多感官整合策略。* 科学方法：这项研究将使用最先进的沉浸式虚拟现实实验室与运动平台相结合进行。这些设施使我们能够系统地操纵提供给每个感官通道的信息，并在感官系统之间产生微妙的冲突。我们将在被动自我运动任务（即运动模拟器上的方向估计）和主动自我运动任务（即在跑步机上行走时的行进距离估计）期间使用完善的心理物理学范例。影响：这些研究将在多感觉整合领域产生重大的全球性理论影响。他们将对自我运动感知，空间更新，运动和衰老的文献做出特别相关的贡献。这些研究的长期应用影响也可以在运动康复、模拟器设计和老龄化人口的车辆设计等领域观察到。