权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Identifying and quantifying metabolites of a novel Metarhizium robersil strain

新型绿僵菌 (Metarhizium robersil) 菌株代谢物的鉴定和定量

基本信息

批准号：
548386-2019
负责人：
Henderson, Deborah
金额：
$ 1.82万
依托单位：
Kwantlen Polytechnic University
依托单位国家：
加拿大
项目类别：
Applied Research and Development Grants - Level 1
财政年份：
2019
资助国家：
加拿大
起止时间：
2019-01-01 至 2020-12-31
项目状态：
已结题

来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=680767
关键词：
Identifying quantifying metabolites novel Metarhizium

项目摘要

The Institute for Sustainable Horticulture (ISH) at Kwantlen Polytechnic University will bring its experience with entomopathogenic fungi to partner with Crop Defenders Ltd. to develop methods and quality controlprotocols for identification and quantification of chemical metabolites produced by a novel isolate ofMetarhizium robertsii (CPD006) under the provisional trade name, NoVil, the company is developing as a newbio-insecticide in Canada. The expertise to identify and quantify secondary metabolites of entomopathogenic fungi does not exist in Canada. Generally, entomopathogenic fungi including Metarhizium robertsii produce a wide variety of biologically active compounds, mostly as products of secondary metabolism, which areinvolved in biocontrol of insect pests and other soil microbiome interactions. Some however are potentially known toxins or mycotoxins and concerns have been raised by regulatory authorities regarding the fate of thesemetabolites in the environment as well as the exposure of workers during mass production. The ISH lab isdeveloping similar protocols to identify and quantify both non-volatile and volatile secondary metabolites of Trichoderma fungi as new biofungicides. This will assist Crop Defenders to bring a valuable newbio-insecticide to the market. The project will increase Kwantlen's capacity to partner with private companies developing natural, fungal-based environmentally protective crop protection products, achieving our goal of supporting sustainability and the green economy and putting more biological products into the hands ofgrowers and pest management personnel. Horticulture students will benefit by exposure to cutting edgeenvironmental products which they will encounter and use in their horticulture careers.

昆特兰理工大学的可持续园艺研究所（ISH）将利用其在昆虫病原真菌方面的经验，与Crop Defenders Ltd.合作开发一种新的罗伯特绿芽胞杆菌（CPD006）分离物产生的化学代谢物的鉴定和定量方法和质量控制协议，该公司正在加拿大开发一种新的生物杀虫剂，临时商品名为NoVil。鉴定和量化昆虫病原真菌次生代谢物的专业知识在加拿大不存在。一般来说，包括罗伯特绿僵菌在内的昆虫病原真菌产生多种生物活性化合物，主要作为次生代谢的产物，参与害虫的生物防治和其他土壤微生物群的相互作用。然而，其中一些是潜在已知的毒素或真菌毒素，监管当局对这些代谢物在环境中的命运以及工人在大规模生产过程中的暴露表示担忧。ISH实验室正在开发类似的方案，以鉴定和量化木霉真菌的非挥发性和挥发性次生代谢物作为新的生物杀菌剂。这将有助于“作物卫士”将一种有价值的新型生物杀虫剂推向市场。该项目将提高Kwantlen与私营公司合作开发天然、真菌为基础的环保作物保护产品的能力，实现我们支持可持续发展和绿色经济的目标，并将更多的生物产品交到种植者和病虫害管理人员手中。园艺专业的学生将受益于接触尖端的环保产品，他们将在园艺职业生涯中遇到并使用这些产品。