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Organoid models of high grade serous ovarian cancer: investigating the effect of homologous recombination mutations on genomic stability

Organoid models of high grade serous ovarian cancer: investigating the effect of homologous recombination mutations on genomic stability
高级别浆液性卵巢癌的类器官模型:研究同源重组突变对基因组稳定性的影响
批准号:
428817
负责人:
Gibbard Evan
金额:
$1.27万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-12-01 至 2020-12-01

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中文摘要
翻译
高级别浆液性卵巢癌(HGS)是最常见和致命的卵巢癌,全世界每年有12万人死于这种疾病。最近,一种名为聚ADP核糖聚合酶(PARP)抑制剂的抗癌新药显示,
英文摘要
"High-grade serous ovarian cancer (HGS) is the most common and lethal form of ovarian cancer, with 120,000 people a year dying worldwide from this disease. Recently, new cancer-killing drugs called poly ADP ribose polymerase (PARP) inhibitors have shown p
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会议论文
Modeling High Grade Serous Ovarian Cancer Using Human Fallopian Tube-Derived Organoids
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海外基金
Journal of Genetics and Genomics