Droplet Microfluidics and Lab-on-a-Chip Technology

基于液滴的Lab-on-a-Chip平台是一种集成了微通道、泵、传感器和加热器的小型化设备，旨在执行从水质到药物发现等应用所需的高通量筛选（HTS）。实现高温超导的载体是在微通道中产生的纳米级液滴，并通过集成元件进行操纵。它的多学科性质需要化学、物理、材料和工程方面的专业知识。在CRC第一届被提名者的研究基础上，她将在拟议的项目中整合这些专业知识，开发功能齐全的集成芯片实验室平台，用于DNA扩增，材料合成和环境监测。

A droplet-based Lab-on-a-Chip platform is a miniaturized device integrated with micro-channels, pumps, sensors and heaters designed to perform high throughput screening (HTS) demanded in applications ranging from water quality to drug discovery. The vehicles for realizing HTS are uniform nanoliter-sized droplets generated in micro-channels and manipulated through integrated components. Its multidisciplinary nature requires expertise in chemistry, physics, materials and engineering. Building upon the research from the nominees first term of CRC, she will assemble this range of expertise in the proposed program to develop fully functional and integrated Lab-on-a-Chip platforms for applications in DNA amplification, material synthesis and environmental monitoring.