课题基金 / 基金详情

Supplementation of folic acid or methyltetrahydrofolate to reduce developmental anomalies in a new mouse model for the MTHFR 677C>T polymorphism

Supplementation of folic acid or methyltetrahydrofolate to reduce developmental anomalies in a new mouse model for the MTHFR 677C>T polymorphism
补充叶酸或甲基四氢叶酸可减少 MTHFR 677C>T 多态性新小鼠模型的发育异常
批准号：
419078
负责人：
Rozen Rima
金额：
$61.58万
依托单位：
Research Institute of the McGill University Health Centre
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2020
资助国家：
加拿大
项目状态：
未结题
起止时间：
2020-03-01 至 2025-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=419078&lang=en
关键词：
Developmental Anomalies Folate Metabolism Folic Acid Gene-Nutrient Interactions Genetic Polymorphism Methyltetrahydrofolate Mthfr

项目摘要

项目成果

Rozen Rima的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Neural tube defects (NTD) are due to inadequate dietary folate. NTD rate has decreased via folic acid (FA) food fortification and consumption of FA-containing vitamins. A common genetic change is a 677C>T mutation in methylenetetrahydrofolate reductase
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Adequate intake of choline in pregnancy may be critical for MTHFD1 synthetase deficiency, a common genetic variant in folate metabolism
Methylenetetrahydrofolate reductase (MTHFR) and multifactorial diseases
19.98CIHR Health Professional Student Research Award vouchers.
  • 批准号：
    234961
  • 项目类别：
    Summer Student Programs
  • 资助金额：
    $6.19万
  • 财政年份：
    2012
  • 负责人：
    Rozen Rima
  • 依托单位：
    McGill University
Trifunctional folate-metabolizing enzyme MTHFD1: impact on birth defects and cancer
海外基金