Understanding interactions between pain, body perception and motor control.
了解疼痛、身体知觉和运动控制之间的相互作用。
基本信息
- 批准号:RGPIN-2019-06532
- 负责人:
- 金额:$ 4.74万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2019
- 资助国家:加拿大
- 起止时间:2019-01-01 至 2020-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
If you ever hit your thumb with a hammer, your first reaction was probably to quickly withdraw your hand, and look at your thumb. At this point, you might have been surprised to realize that it looked pretty normal, while it felt to you like it had double in size. Afterwards, you might have adapted your motor strategy, first because your thumb still felt awkward holding the nail, and second because you were somewhat anxious about the fact that your action might generate more pain. This illustrates the complexity of the relationships between the pain system and the sensorimotor system. One the one hand, pain can impact on the way we perceive our body as well as on our motor behavior. Indeed, it can induce various distortions in body perception, such as changes in the perception of size, shape, position and movement of the limbs. On the other hand, visual, tactile and proprioceptive information about our body can affect our perception of pain. ***The long-term objective of my research program is to investigate these interactions between the pain system and the sensorimotor system in order to better understand how pain impacts on body perception and action and vice versa. Over the next five years, I will test the hypothesis that the presence of pain (or even its anticipation) impairs the ability of the brain to perceive the position and movement of the limbs, as well as to predict the consequences of motor commands. According to this hypothesis, people should rely more heavily on visual information to guide their motor actions when they are in pain. ***This will be assessed using a robotic system combined with a 2D virtual environment that allows the provision of altered visual feedback about the arms and their movements, the application of controlled perturbations and the precise measurement of motor performance. We will also measure the activity of brain regions involved in the control and perception of the body (with transcranial magnetic stimulation and electroencephalography) to understand the underlying neurophysiological mechanisms.***This research program will provide fundamental knowledge on how the human brain integrates information from different sources to create a unified representation of the body. It will benefit a number of fields including virtual reality, sports training, injury prevention and rehabilitation. It will also provide outstanding training opportunities for students from various disciplines.**
如果你曾经用锤子砸到拇指,你的第一反应可能是迅速收回你的手,看看你的拇指。在这一点上,你可能会惊讶地意识到,它看起来很正常,而你觉得它有两倍的大小。之后,你可能会调整你的运动策略,首先是因为你的拇指仍然觉得握着钉子很尴尬,其次是因为你有点担心你的动作可能会产生更多的疼痛。这说明了疼痛系统和感觉运动系统之间关系的复杂性。一方面,疼痛会影响我们感知身体的方式以及运动行为。事实上,它可以引起身体感知的各种扭曲,例如对肢体大小、形状、位置和运动的感知的变化。另一方面,关于我们身体的视觉、触觉和本体感受信息会影响我们对疼痛的感知。* 我的研究计划的长期目标是研究疼痛系统和感觉运动系统之间的相互作用,以便更好地了解疼痛如何影响身体感知和行动,反之亦然。在接下来的五年里,我将检验一个假设,即疼痛的存在(甚至是对疼痛的预期)会削弱大脑感知肢体位置和运动的能力,以及预测运动指令的后果的能力。根据这一假设,人们在疼痛时应该更多地依赖视觉信息来指导他们的运动动作。* 这将使用机器人系统与2D虚拟环境相结合进行评估,该虚拟环境允许提供关于手臂及其运动的改变的视觉反馈,受控扰动的应用以及运动性能的精确测量。我们还将测量参与身体控制和感知的大脑区域的活动(使用经颅磁刺激和脑电图),以了解潜在的神经生理机制。这项研究计划将提供关于人类大脑如何整合来自不同来源的信息以创建身体的统一表示的基础知识。它将使虚拟现实、运动训练、伤害预防和康复等多个领域受益。它还将为来自不同学科的学生提供出色的培训机会。
项目成果
期刊论文数量(0)
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Mercier, Catherine其他文献
Effect of Single-Session Repetitive Transcranial Magnetic Stimulation Applied Over the Hand Versus Leg Motor Area on Pain After Spinal Cord Injury
- DOI:
10.1177/1545968313484810 - 发表时间:
2013-09-01 - 期刊:
- 影响因子:4.2
- 作者:
Jette, Fanny;Cote, Isabelle;Mercier, Catherine - 通讯作者:
Mercier, Catherine
Exploring the Relationships Between Altered Body Perception, Limb Position Sense, and Limb Movement updates Sense in Complex Regional Pain Syndrome
- DOI:
10.1016/j.jpain.2018.07.008 - 发表时间:
2019-01-01 - 期刊:
- 影响因子:4
- 作者:
Brun, Clementine;Giorgi, Nicolas;Mercier, Catherine - 通讯作者:
Mercier, Catherine
Anodal Transcranial Direct-Current Stimulation to Enhance Rehabilitation in Individuals With Rotator Cuff Tendinopathy: A Triple-Blind Randomized Controlled Trial
- DOI:
10.2519/jospt.2018.7871 - 发表时间:
2018-07-01 - 期刊:
- 影响因子:6.1
- 作者:
Belley, Amelie Fournier;Mercier, Catherine;Roy, Jean-Sebastien - 通讯作者:
Roy, Jean-Sebastien
Do nociceptive stimulation intensity and temporal predictability in fluence pain -induced corticospinal excitability modulation?
- DOI:
10.1016/j.neuroimage.2020.116883 - 发表时间:
2020-08-01 - 期刊:
- 影响因子:5.7
- 作者:
Neige, Cecilia;Brun, Clementine;Mercier, Catherine - 通讯作者:
Mercier, Catherine
Effect of repetitive afferent electrical stimulation of the lower limb on corticomotor excitability and implications for rehabilitation
- DOI:
10.1016/j.jocn.2012.02.049 - 发表时间:
2013-03-01 - 期刊:
- 影响因子:2
- 作者:
Leonard, Guillaume;Mercier, Catherine;Tremblay, Louis E. - 通讯作者:
Tremblay, Louis E.
Mercier, Catherine的其他文献
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{{ truncateString('Mercier, Catherine', 18)}}的其他基金
Understanding interactions between pain, body perception and motor control.
了解疼痛、身体知觉和运动控制之间的相互作用。
- 批准号:
RGPIN-2019-06532 - 财政年份:2022
- 资助金额:
$ 4.74万 - 项目类别:
Discovery Grants Program - Individual
Understanding interactions between pain, body perception and motor control.
了解疼痛、身体知觉和运动控制之间的相互作用。
- 批准号:
RGPIN-2019-06532 - 财政年份:2021
- 资助金额:
$ 4.74万 - 项目类别:
Discovery Grants Program - Individual
Understanding interactions between pain, body perception and motor control.
了解疼痛、身体知觉和运动控制之间的相互作用。
- 批准号:
RGPIN-2019-06532 - 财政年份:2020
- 资助金额:
$ 4.74万 - 项目类别:
Discovery Grants Program - Individual
Effect of acute pain on the plastic potential of the sensorimotor cortex
急性疼痛对感觉运动皮层可塑性潜力的影响
- 批准号:
355896-2012 - 财政年份:2018
- 资助金额:
$ 4.74万 - 项目类别:
Discovery Grants Program - Individual
Journées annuelles des chantiers de travail du CIRRIS
CIRRIS 歌手年鉴
- 批准号:
522534-2017 - 财政年份:2017
- 资助金额:
$ 4.74万 - 项目类别:
Connect Grants Level 2
Effect of acute pain on the plastic potential of the sensorimotor cortex
急性疼痛对感觉运动皮层可塑性潜力的影响
- 批准号:
355896-2012 - 财政年份:2017
- 资助金额:
$ 4.74万 - 项目类别:
Discovery Grants Program - Individual
Effect of acute pain on the plastic potential of the sensorimotor cortex
急性疼痛对感觉运动皮层可塑性潜力的影响
- 批准号:
355896-2012 - 财政年份:2016
- 资助金额:
$ 4.74万 - 项目类别:
Discovery Grants Program - Individual
Effect of acute pain on the plastic potential of the sensorimotor cortex
急性疼痛对感觉运动皮层可塑性潜力的影响
- 批准号:
355896-2012 - 财政年份:2015
- 资助金额:
$ 4.74万 - 项目类别:
Discovery Grants Program - Individual
Effect of acute pain on the plastic potential of the sensorimotor cortex
急性疼痛对感觉运动皮层可塑性潜力的影响
- 批准号:
355896-2012 - 财政年份:2014
- 资助金额:
$ 4.74万 - 项目类别:
Discovery Grants Program - Individual
Integration of a scalable avatar-based virtual feedback system to a robotized exoskeleton for application to chronic pain rehabilitation
将可扩展的基于化身的虚拟反馈系统集成到机器人外骨骼中,用于慢性疼痛康复
- 批准号:
477404-2014 - 财政年份:2014
- 资助金额:
$ 4.74万 - 项目类别:
Engage Grants Program
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Understanding interactions between pain, body perception and motor control.
了解疼痛、身体知觉和运动控制之间的相互作用。
- 批准号:
RGPIN-2019-06532 - 财政年份:2022
- 资助金额:
$ 4.74万 - 项目类别:
Discovery Grants Program - Individual