Evolutionary Cell Biology

进化细胞生物学

• 批准号: 1000230987-2015
• 负责人: Dacks, Joel
• 金额: $ 7.29万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=695773
• 关键词: Evolutionary; Cell; Biology

Our cells, eukaryotic cells, are divided into compartments: bacterial cells arent. This organizational difference influences how cells work, allowing eukaryotes to grow into the vast biodiversity observed today. Scientists know a great deal about how this organization operates today: we know a lot less about how it arose. Particularly mysterious are the membrane-trafficking compartments, responsible for moving material into, out of and around the cell. The mandate of this CRC is to continue applying computational techniques and microbial genomics, looking back two billion years, to understand the fundamental biological mechanisms by which the membrane-trafficking compartments, and our cells overall, evolved.

我们的细胞，真核细胞，被分成不同的部分：细菌细胞没有。这种组织差异影响了细胞的工作方式，使真核生物能够成长为今天观察到的巨大生物多样性。科学家们对这个组织今天是如何运作的知道很多，但对它是如何产生的却知之甚少。特别神秘的是膜运输隔间，负责将物质移入，移出和围绕细胞。该CRC的任务是继续应用计算技术和微生物基因组学，回顾20亿年，以了解膜运输区室和我们的细胞整体进化的基本生物学机制。