It takes two to tango: Parental obesity and sex-specific impacts on placental development

探戈需要两个人：父母肥胖和性别对胎盘发育的影响

• 批准号: 435572
• 负责人: Sloboda Deborah M
• 金额: $ 62.42万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-10-01 至 2025-10-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=435572&lang=en
• 关键词: Early Origins Of Disease; Fetal Development; Metabolism; Obesity; Placenta; Sex

Maternal factors, including obesity, increase the risk of obesity in her offspring - independent of postnatal diet and lifestyle - in a sex-specific manner where males and females show different metabolic outcomes. Some of this risk is due to poor placent

母亲的因素，包括肥胖，增加了她的后代肥胖的风险--与出生后的饮食和生活方式无关--以一种性别特有的方式，即男性和女性表现出不同的代谢结果。这种风险部分是由于胎盘不良造成的。