Aptasensor SPR testing platform for COVID-19

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Early detection of COVID-19 is critical to halting the spread of the novel corona virus. Current virus detection technologies are based on genetic or immunological assays, however, these techniques require costly instrumentation, a lab setting, extensive reagents, and specialized technical expertise, as well as long response time. These methods are not amendable to an on-site application, or as a ready-to-use kit by a non-technician. The research proposed here aims to develop diagnostic technologies for on-site applications in public settings. The novel diagnostic platform would maintain sensitivity analogous to PCR, but would offer a cost-effective user-friendly tool to untrained scientists for detection of the COVID-19 in public locations. This level of access would lead to early detection of COVID-19 infections, thereby helping to prevent the virus from spreading during pandemic. The goals of the proposed partnership are to design aptamers for Surface Plasmon Resonance detection of COVID-19 proteins. This partnership will lead to the first ever technology based on the novel SPR aptasensor for detection of proteins of COVID-19.