Investigating the role of glutamate in mitogen-activated protein kinase inhibitor-resistant melanoma and its effects on CD8+ T cell subsets and response to anti-PD1 immunotherapy
Investigating the role of glutamate in mitogen-activated protein kinase inhibitor-resistant melanoma and its effects on CD8+ T cell subsets and response to anti-PD1 immunotherapy
研究谷氨酸在丝裂原激活蛋白激酶抑制剂耐药性黑色素瘤中的作用及其对 CD8 T 细胞亚群和抗 PD1 免疫治疗反应的影响
批准号：
449743
负责人：
Kates Meghan
金额：
$1.27万
依托单位：
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2020
资助国家：
加拿大
项目状态：
已结题
起止时间：
2020-12-01 至 2021-12-01
中文摘要
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英文摘要
Melanoma skin cancer is easily treatable on early detection, but less than half of patients with metastatic disease survive past two years. About 50% of melanoma patients have an alteration in the protein BRAF that increases cell growth and replication. T
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