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Systematic mapping of the global ARF network interactome by BioID coupled to functional studies to reveal novel biological functions

Systematic mapping of the global ARF network interactome by BioID coupled to functional studies to reveal novel biological functions
通过 BioID 与功能研究相结合，对全球 ARF 网络相互作用组进行系统绘图，以揭示新的生物学功能
批准号：
444933
负责人：
Côt Jean-François
金额：
$66.32万
依托单位：
Institut de recherches cliniques de Montral
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2021
资助国家：
加拿大
项目状态：
未结题
起止时间：
2021-04-01 至 2026-04-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=444933&lang=en
关键词：
Arf Gtpases Effector Proteins Fly Genetics Ras Gtpases Signal Transduction Structural Biology Trafficking

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The RAS superfamily is composed of nearly 150 proteins divided into RAS, RHO, ARF and RAB. The ARF family is composed of 30 proteins and approximately 42 regulators involved in basic cellular functions of membrane trafficking. Many of these proteins are c
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