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Unraveling the molecular mechanisms that promote replication stress and resistance to chemoradiation in oropharyngeal cancer caused by human papillomavirus

Unraveling the molecular mechanisms that promote replication stress and resistance to chemoradiation in oropharyngeal cancer caused by human papillomavirus
揭示人乳头瘤病毒引起的口咽癌复制应激和放化疗抗性的分子机制
批准号:
452085
负责人:
Fradet-Turcotte Amlie
金额:
$64.93万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01

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中文摘要
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英文摘要
Human papillomaviruses (HPV) infect undifferentiated stem cells of our skin. While our immune system clears most of these infections, the persistence of HPV lead to the development of cervical and oropharyngeal cancers (OPCs). Over the last decade, the nu
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Canada Research Chair - Tier 2
  • 批准号:
    454221
  • 项目类别:
  • 资助金额:
    $36.43万
  • 财政年份:
    2021
  • 负责人:
    Fradet-Turcotte Amlie
  • 依托单位:
Characterization of PTM-associated mutations that alter signaling network in breast and ovarian cancers.
  • 批准号:
    407419
  • 项目类别:
    Operating Grants
  • 资助金额:
    $4.37万
  • 财政年份:
    2019
  • 负责人:
    Fradet-Turcotte Amlie
  • 依托单位:
Defining the molecular basis of chemoradiation sensitivity in HPV+ head and neck cancers.
  • 批准号:
    358025
  • 项目类别:
    Operating Grants
  • 资助金额:
    $50.71万
  • 财政年份:
    2016
  • 负责人:
    Fradet-Turcotte Amlie
  • 依托单位:
Canada Research Chair - Tier 2
  • 批准号:
    351564
  • 项目类别:
  • 资助金额:
    $36.43万
  • 财政年份:
    2015
  • 负责人:
    Fradet-Turcotte Amlie
  • 依托单位:
海外基金