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Characterisation of the recruitment and functions of 53BP1 at DNA damage sites

Characterisation of the recruitment and functions of 53BP1 at DNA damage sites
DNA 损伤位点 53BP1 的招募和功能的表征
批准号:
242507
负责人:
Fradet-Turcotte Amlie
金额:
$9.83万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-10-01 至 2014-10-01

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中文摘要
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英文摘要
DNA double-stranded breaks (DSBs) are induced by exposure to environmental factors such as sunlight and ionizing radiation (IR), the agent used in cancer radiotherapy, but they also occur in a programmed manner in processes such as development and aging.
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Canada Research Chair - Tier 2
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    454221
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    $36.43万
  • 财政年份:
    2021
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  • 依托单位:
Unraveling the molecular mechanisms that promote replication stress and resistance to chemoradiation in oropharyngeal cancer caused by human papillomavirus
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    2021
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Characterization of PTM-associated mutations that alter signaling network in breast and ovarian cancers.
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    407419
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    $4.37万
  • 财政年份:
    2019
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Defining the molecular basis of chemoradiation sensitivity in HPV+ head and neck cancers.
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    358025
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