Peeling off the secrets of Populus trichocarpa defences

揭开毛果杨防御的秘密

基本信息

  • 批准号:
    RGPIN-2019-04772
  • 负责人:
  • 金额:
    $ 2.4万
  • 依托单位:
  • 依托单位国家:
    加拿大
  • 项目类别:
    Discovery Grants Program - Individual
  • 财政年份:
    2020
  • 资助国家:
    加拿大
  • 起止时间:
    2020-01-01 至 2021-12-31
  • 项目状态:
    已结题

项目摘要

Plant specialized metabolites (traditionally called secondary metabolites) are compounds whose biosynthesis is restricted to specific lineages and play key roles in ecological interactions. Plants acquire the ability to synthesize new specialized metabolites as a strategy to cope with biotic and abiotic stress when the environment changes. The long-term vision of my research program is to understand this biochemical response by exploring the natural diversity of specialized metabolites, figuring out how new metabolites are synthesized, and ultimately deciphering how they help the plant thrive in a challenging environment. My proposed NSERC research program focuses on waxes and terpenes from the black cottonwood tree (Populus trichocarpa, poplar) as model systems. Among the traits that plants use to deter invaders, the cuticle and the waxes contained within the cuticle constitute the first barrier against a hostile environment. To investigate the role of the cuticular waxes and individual wax components, we will exploit the extensive variation in wax composition and abundance present in a collection of naturally occurring genotypes of P. trichocarpa. We have shown that alkenes, a type of organic compound, are major components of the wax of black cottonwood leaves. Interestingly, despite the many industrial uses of alkenes, the way by which they are produced in plants was completely unknown. My previous work identified the first enzyme involved in the biosynthesis of alkenes. This discovery has opened the doors to the study of a new pathway for the biosynthesis of cuticular waxes. However, there are still several key areas that need to be investigated if we want to harness cuticular wax diversity as a protection mechanism against environmental stress. In the proposed research we will address the following short-term objectives: 1- Identify and characterize the genes involved in regulating and producing alkenes; 2- Investigate the role of cuticular waxes against environmental stresses; and 3- Develop the tools and methods required to study terpenes, another group of defence compounds of the black cottonwood tree. Even though the underlying question driving my research is why plants synthesize specialized metabolites, the knowledge generated has potential applications in crop improvement and industry. By understanding the biosynthesis and ecological role of specialized metabolites we will be able to breed or engineer plants better adapted to specific environments. Moreover, waxes and terpenes have commercial value as pharmaceuticals, pesticides, food additives, and biofuels. This program will require a multi-disciplinary approach that will train highly qualified personnel in genomics, biochemistry, analytical chemistry, plant physiology and biotechnology.
植物特化代谢物(传统上称为次生代谢物)是一类生物合成局限于特定谱系,在生态相互作用中起关键作用的化合物。当环境发生变化时,植物获得了合成新的专门代谢物的能力,作为应对生物和非生物胁迫的一种策略。我的研究计划的长期愿景是通过探索特殊代谢物的自然多样性来理解这种生化反应,弄清楚新的代谢物是如何合成的,并最终破译它们如何帮助植物在具有挑战性的环境中茁壮成长。我提出的NSERC研究计划侧重于黑棉树(Populus trichocarpa,杨树)的蜡和萜烯作为模型系统。

项目成果

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GonzalesVigil, Eliana其他文献

GonzalesVigil, Eliana的其他文献

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{{ truncateString('GonzalesVigil, Eliana', 18)}}的其他基金

Peeling off the secrets of Populus trichocarpa defences
揭开毛果杨防御的秘密
  • 批准号:
    RGPIN-2019-04772
  • 财政年份:
    2022
  • 资助金额:
    $ 2.4万
  • 项目类别:
    Discovery Grants Program - Individual
Peeling off the secrets of Populus trichocarpa defences
揭开毛果杨防御的秘密
  • 批准号:
    RGPIN-2019-04772
  • 财政年份:
    2021
  • 资助金额:
    $ 2.4万
  • 项目类别:
    Discovery Grants Program - Individual
Peeling off the secrets of Populus trichocarpa defences
揭开毛果杨防御的秘密
  • 批准号:
    DGECR-2019-00172
  • 财政年份:
    2019
  • 资助金额:
    $ 2.4万
  • 项目类别:
    Discovery Launch Supplement
Peeling off the secrets of Populus trichocarpa defences
揭开毛果杨防御的秘密
  • 批准号:
    RGPIN-2019-04772
  • 财政年份:
    2019
  • 资助金额:
    $ 2.4万
  • 项目类别:
    Discovery Grants Program - Individual

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