Biomolecular Imaging System for Nanomedicine and Chemical Biology Applications in Pharmaceutical Sciences

英属哥伦比亚大学药物科学学院的纳米医学和化学生物学研究小组有兴趣通过获得最先进的激光扫描仪系统，迅速扩大他们在各个研究领域的成像能力。该激光扫描系统将被安置在UBC温哥华校区制药科学大楼内的研究基础设施集群中，以满足我们科学家的多样化需求，是多功能和必要的设备，具有目前可用的最广泛的定量成像模式。除了常规用于蛋白质检测的化学发光外，该激光扫描仪的另一个关键特征是其四色（蓝色，绿色，红色和近红外）荧光检测和定量，允许对复杂样品进行多路成像。激光扫描仪还能够通过无膜放射自显影进行放射性信号检测，具有目前可用的最宽线性动态。所有这些先进的成像技术将使我们能够通过分子、细胞和组织可视化的强大力量将我们的科学带入生活。这台多用途多用户激光成像仪的收购将有助于提升我们研究团队的卓越水平，并为许多加拿大研究人员提供各种职业水平的培训机会。

The Nanomedicine and Chemical Biology research group within the Faculty of Pharmaceutical Sciences at the University of British Columbia is interested in rapidly expanding their imaging capabilities in various areas of research by acquiring a state-of-the-art laser scanner system. This laser scanning system, which will be housed in a research infrastructure cluster within the Pharmaceutical Sciences building on the UBC Vancouver campus to fulfill the diverse needs of our scientists, is versatile and essential equipment with the broadest range of quantitative imaging modalities currently available. In addition to chemiluminescence that is routinely used for protein detection on Western blots to identify specific proteins, another key feature unique for this laser scanner is its four-colour (blue, green, red, and near infrared) fluorescence detection and quantification that allows for multiplexed imaging for complex samples. The laser scanner is also capable of radioactive signal detection through filmless autoradiography with the widest linear dynamic currently available. All of these advanced imaging techniques will enable us to bring our science to life through the awesome power of molecular, cellular, and tissue visualization. The acquisition of this multi-use and multi-user laser imager will help elevate the excellence of our research team and provide accessible training opportunities for many Canadian researchers at all career levels.