Sulfur in Inorganic Fluorine Chemistry and the Development of a New Class of Weakly Coordinating Anions

无机氟化学中的硫和一类新型弱配位阴离子的开发

• 批准号: 261340-2013
• 负责人: Gerken, Michael
• 金额: $ 2.48万
• 依托单位: University of Lethbridge
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=718975
• 关键词: Sulfur; Inorganic; Fluorine; Chemistry; Development

Chemistry of the element fluorine has experienced a remarkable renaissance in the last decade, with spectacular discoveries and the outstanding utility of organofluorine compounds in the pharmaceutical industry. However, incorporation of fluorine almost always requires the use of reactive inorganic fluorinating agents, and to ensure that the full range of fluorinated products is maintained, new fluorinating reagents are always needed. The current proposal focuses on inorganic fluorine chemistry and is exploring fundamental structural and reactivity questions, as well as potential applications of inorganic fluorides. The inorganic fluorine chemistry group in Lethbridge is one of the few groups in the world that can handle highly reactive fluorine chemicals and train students in this important field of chemistry. The new compounds that will be made in this proposed research represent powerful new fluorinating reagents. The proposed research will target three types of fluorine compounds: (i) rhenium sulfide fluorides, (ii) inorganic compounds with pentafluorosulfanyl (-SF5) groups, and (iii) large, weakly coordinating anions. Rhenium sulfide fluorides are reactive compounds that are interesting because of their structural features and of the catalytic reactivity of rhenium sulfide, which were found to have potential as hydrodesulfurization catalysts in the petrochemical industry. Fluoroorganic chemists succeeded in preparing organic SF5 compounds that have uses, for example, as pesticides in agrochemistry and solvents for polymers. Essentially no compounds with SF5 directly attached to a metal are known. Such metal compounds could have significant potential as facile reagents to introduce SF5 groups into organic systems. Weakly coordinating anions have already attracted vast attention in industry. This proposal targets a new class of such anions that could provide advantages to the currently used weakly coordinating anions. Applications of such anions range from lithium ion battery applications to ionic liquids. Ionic liquids are important to further develop "green" chemistry since they are recyclable, do not have any significant vapour pressure and will not cause atmospheric pollution because of evaporation.

在过去的十年中，氟元素的化学经历了一次非凡的复兴，有机氟化合物在制药工业中的惊人发现和杰出用途。然而，氟的掺入几乎总是需要使用反应性无机氟化剂，并且为了确保保持氟化产品的全范围，总是需要新的氟化试剂。目前的建议集中在无机氟化学，并正在探索基本的结构和反应性问题，以及无机氟化物的潜在应用。莱斯布里奇的无机氟化学小组是世界上少数几个能够处理高活性氟化学品并培养这一重要化学领域学生的小组之一。在这项拟议的研究中将制造的新化合物代表了强大的新氟化试剂。拟议的研究将针对三种类型的氟化合物：（i）三氟硫醚氟化物，（ii）具有五氟硫烷基（-SF 5）基团的无机化合物，以及（iii）大的弱配位阴离子。硫化铼氟化物由于其结构特征和硫化铼的催化活性而引起人们的兴趣，其被发现在石化工业中具有作为加氢脱硫催化剂的潜力。氟有机化学家成功地制备了有机SF 5化合物，这些化合物可用作农业化学中的农药和聚合物的溶剂。基本上没有已知的SF 5直接连接到金属上的化合物。这种金属化合物可能具有作为将SF 5基团引入到有机体系中的简易试剂的显著潜力。弱配位阴离子在工业上已经引起了广泛的关注。该提议针对一类新的此类阴离子，其可以为目前使用的弱配位阴离子提供优势。这种阴离子的应用范围从锂离子电池应用到离子液体。离子液体对于进一步发展“绿色”化学是重要的，因为它们是可回收的，不具有任何显著的蒸气压，并且不会由于蒸发而引起大气污染。