Exploiting microtubule-dependent DNA double-strand break repair to target BRCA1-deficient breast cancer
Exploiting microtubule-dependent DNA double-strand break repair to target BRCA1-deficient breast cancer
批准号:
467070
负责人:
Hundal Anisha
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2021
资助国家:
加拿大
项目状态:
已结题
起止时间:
2021-12-01 至 2022-12-01
中文摘要
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英文摘要
Two major pathways cells use to repair DNA double-strand breaks (DSB) are homologous recombination (HR) and non-homologous end joining (NHEJ). BRCA1 steers cells toward HR and mutations in BRCA1 increase the likelihood of breast cancer. Additionally, a co
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