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Targeting DNA repair mechanisms by nanoparticles of RNA and radiosensitizer for enhancing treatment of brain metastases of breast cancer

Targeting DNA repair mechanisms by nanoparticles of RNA and radiosensitizer for enhancing treatment of brain metastases of breast cancer
通过 RNA 纳米颗粒和放射增敏剂靶向 DNA 修复机制,增强乳腺癌脑转移的治疗
批准号:
488264
负责人:
Wu Xiao Yu S
金额:
$4.55万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
已结题
起止时间:
2023-02-01 至 2024-02-01

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中文摘要
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英文摘要
Breast cancer is the most prevalent malignancy and the second leading cause of cancer-related deathsin women in Canada and worldwide. Breast cancer brain metastasis occursin 15–35% of all metastatic breast cancer leading to short survival time and poor qu
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Multitargeted Nanomedicine of Synergistic Drug Combinations for Metastatic Breast Cancer Therapy
  • 批准号:
    407988
  • 项目类别:
    Operating Grants
  • 资助金额:
    $36.5万
  • 财政年份:
    2019
  • 负责人:
    Wu Xiao Yu S
  • 依托单位:
Development of a Smart Tumor-Activated Nanodiagnostic System for Sensitive Detection of Solid Tumors and Metastases
  • 批准号:
    390372
  • 项目类别:
    Operating Grants
  • 资助金额:
    $34.27万
  • 财政年份:
    2018
  • 负责人:
    Wu Xiao Yu S
  • 依托单位:
Engineering Transformable Polymer-lipid Nanoparticles for Cascade Drug Delivery to Brain Cancer Cells
  • 批准号:
    305426
  • 项目类别:
    Operating Grants
  • 资助金额:
    $37.31万
  • 财政年份:
    2014
  • 负责人:
    Wu Xiao Yu S
  • 依托单位:
Preclinical evaluation of multifunctional polymer nanoparticles for targeted brain cancer therapy
  • 批准号:
    293919
  • 项目类别:
    Operating Grants
  • 资助金额:
    $11.66万
  • 财政年份:
    2013
  • 负责人:
    Wu Xiao Yu S
  • 依托单位:
海外基金