Assessing contractile dysfunction due to SARS-CoV-2 infection in a heart-on-a-chip platform

在芯片心脏平台中评估 SARS-CoV-2 感染引起的收缩功能障碍

• 批准号: 458272
• 负责人: Smith Jacob B
• 金额: $ 7.65万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-11-01 至 2024-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=458272&lang=en
• 关键词: Angiotensin Ii; Biological Modeling; Caradiovascular; Heart; Image Analysis; Machine Learning; Microfabrication; Organ-On-A-Chip; Sars-Cov-19; Tissue Engineering

Introduction: The recent worldwide COVID-19 pandemic is known for its damaging effects on the lungs of infected patients, however new research is starting to show that it can also damage the heart. Using advanced biological methods, patient stem cells can

导语：最近全球范围内的COVID-19大流行以其对受感染患者肺部的破坏性影响而闻名，但新的研究开始表明，它也会损害心脏。使用先进的生物学方法，患者干细胞可以