NUMERICAL TOOLS FOR NEW CELL BIOLOGICAL MODELING CAPABILITIES IN VCELL

VCELL 中新细胞生物建模功能的数值工具

• 批准号: 7956397
• 负责人: BORIS SLEPCHENKO
• 金额: $ 3.25万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7956397
• 关键词: Algorithms; Biological Models; Biomechanics; Cell model; Cells; Computer Retrieval of Information on Scientific Projects Database; Diffusion; Electrophysiology (science); Equation; Funding; Grant; Institution; Modeling; Reaction; Research; Research Personnel; Resources; Solutions; Source; System; United States National Institutes of Health; tool

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project is aimed at implementing new capabilities within VCell for modeling cell phenomena. In particular, algorithms for solving linear elliptic (Poisson-type) equations will be implemented that are required for modeling effects of cell biomechanics and electrophysiology. Elliptic solvers are also required to find a steady-state solution of a reaction-diffusion system. In addition, other new capabilities, such as different types of boundary conditions, block solvers, etc., will be implemented.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 该项目的目标是在Vcell中实现用于模拟细胞现象的新功能。特别是，将实现解线性椭圆(泊松类型)方程的算法，这是对细胞生物力学和电生理学的影响进行建模所必需的。求反应扩散系统的稳态解也需要椭圆求解器。此外，还将实现其他新功能，如不同类型的边界条件、块求解器等。