NUMERICAL TOOLS FOR NEW CELL BIOLOGICAL MODELING CAPABILITIES IN VCELL

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 中心，但不一定是研究者所在的机构。 该项目旨在实现VCell中的新功能，用于对细胞现象进行建模。特别是，将实施用于求解线性椭圆（泊松型）方程的算法，这是细胞生物力学和电生理学建模效果所需的。椭圆求解器也需要找到反应扩散系统的稳态解。此外，其他新功能，如不同类型的边界条件、块求解器等，将得到执行。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project is aimed at implementing new capabilities within VCell for modeling cell phenomena. In particular, algorithms for solving linear elliptic (Poisson-type) equations will be implemented that are required for modeling effects of cell biomechanics and electrophysiology. Elliptic solvers are also required to find a steady-state solution of a reaction-diffusion system. In addition, other new capabilities, such as different types of boundary conditions, block solvers, etc., will be implemented.