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Exploring the effects of manipulating the transcriptional regulatory networks of tissue-resident lung macrophage populations in mouse models of pulmonary fibrosis

Exploring the effects of manipulating the transcriptional regulatory networks of tissue-resident lung macrophage populations in mouse models of pulmonary fibrosis
探索操纵肺纤维化小鼠模型中组织驻留肺巨噬细胞群转录调控网络的影响
批准号：
466613
负责人：
Charette Emilie
金额：
$1.27万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-12-01 至 2022-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=466613&lang=en
关键词：
Adeno-Associated Viruses Bioinformatics Crispr-Cas9 Idiopathic Pulmonary Fibrosis Lung Macrophages Machine Learning Next Generation Sequencing Transcriptional Regulatory Networks

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中文摘要
翻译
间质性肺病（ILD）是一个广义的术语，指的是几种引起肺纤维化的疾病，这种疾病会增加肺僵硬，使呼吸困难。特发性肺纤维化（Idiopathic pulmonary fibrosis， IPF）是最常见的肺纤维化之一，具有严重的危害
英文摘要
Interstitial lung disease (ILD) is a broad term referring to several diseases causing lung fibrosis, which increases lung stiffness, making it harder to breathe. Idiopathic pulmonary fibrosis (IPF) is one of the most common ILDs and has devastating implic
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