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Reconstructing the microbe-host interface in an advanced bioprinted co-culture system to study microbial community contributions to chemotherapy-induced oral mucositis

Reconstructing the microbe-host interface in an advanced bioprinted co-culture system to study microbial community contributions to chemotherapy-induced oral mucositis
在先进的生物打印共培养系统中重建微生物-宿主界面，以研究微生物群落对化疗引起的口腔粘膜炎的贡献
批准号：
461756
负责人：
Leung Brendan M
金额：
$41.8万
依托单位：
Dalhousie University (Nova Scotia)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2022
资助国家：
加拿大
项目状态：
未结题
起止时间：
2022-03-01 至 2027-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=461756&lang=en
关键词：
Aqueous Two Phase System Bioinformatics Chemotherapy Co-Culture Inflammation Microbiome Oral Mucositis Probiotics Tissue Engineering

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英文摘要
Chemotherapy induced oral mucositis (CIOM) is a painful and debilitating side effect of cancer treatment that affects 20-40% of cancer patients. Chemotherapy kills cancer cells, but it also affects fast growing normal cells in the body, especially those t
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