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Mechanisms of IRF2-driven immune regulation in the tumor microenvironment

Mechanisms of IRF2-driven immune regulation in the tumor microenvironment
IRF2驱动的肿瘤微环境免疫调节机制
批准号:
461659
负责人:
Brooks David
金额:
$81.51万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-03-01 至 2027-03-01

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中文摘要
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英文摘要
Central to immune alterations in the tumor microenvironment (TME) that facilitate tumor growth is the functional attenuation (exhaustion) of CD8 T cells. As a result, restoring function to CD8 T cells so that they can eliminate tumors is currently a main
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会议论文
Type I interferon mediated regulation of chronic virus infection
  • 批准号:
    487143
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2023
  • 负责人:
    Brooks David
  • 依托单位:
Type I interferon mediated regulation of chronic virus infection
  • 批准号:
    487980
  • 项目类别:
    Operating Grants
  • 资助金额:
    $90.0万
  • 财政年份:
    2023
  • 负责人:
    Brooks David
  • 依托单位:
Immune Regulation during Chronic Disease
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