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Development of boron-based inhibitors of the mitochondrial ClpXP protease to combat AML

Development of boron-based inhibitors of the mitochondrial ClpXP protease to combat AML
开发基于硼的线粒体 ClpXP 蛋白酶抑制剂来对抗 AML
批准号:
472460
负责人:
Vahidi Siavash
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-09-01 至 2023-09-01

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中文摘要
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英文摘要
Acute myeloid leukemia (AML) is a type of cancer in which the bone marrow makes abnormal blood cells. The outcome for most AML patients, especially older ones remains poor. Despite advances in the field that include new drug targets, coupled with an incre
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Disrupting the Pathogens' Communication Lines: The Next Frontier in Combating Antimicrobial Resistance
  • 批准号:
    492393
  • 项目类别:
  • 资助金额:
    $0.15万
  • 财政年份:
    2023
  • 负责人:
    Vahidi Siavash
  • 依托单位:
Developing allosteric inhibitors of mitochondrial ClpP protease for acute myeloid leukemia
  • 批准号:
    489309
  • 项目类别:
    Operating Grants
  • 资助金额:
    $83.32万
  • 财政年份:
    2023
  • 负责人:
    Vahidi Siavash
  • 依托单位:
The Bhagirath Singh Early Career Prize in Infection and Immunity: Mechanisms of Allosteric Regulation of M. tuberculosis Proteasome Function
  • 批准号:
    446144
  • 项目类别:
    Operating Grants
  • 资助金额:
    $0.91万
  • 财政年份:
    2020
  • 负责人:
    Vahidi Siavash
  • 依托单位:
Mechanisms of Allosteric Regulation of M. tuberculosis Proteasome Function
  • 批准号:
    433624
  • 项目类别:
    Operating Grants
  • 资助金额:
    $60.75万
  • 财政年份:
    2020
  • 负责人:
    Vahidi Siavash
  • 依托单位:
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