Stage-specific treatment of human non-alcoholic fatty liver disease: elucidating the precise mechanisms of actions of glucagon-like peptide-1 receptor agonists and novel anti-fibrosis molecules
Stage-specific treatment of human non-alcoholic fatty liver disease: elucidating the precise mechanisms of actions of glucagon-like peptide-1 receptor agonists and novel anti-fibrosis molecules
批准号:
468757
负责人:
Gaisano Herbert Y
金额:
$81.37万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-09-01 至 2027-09-01
中文摘要
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英文摘要
Non-alcoholic Fatty Liver Disease (NAFLD) is present in 30% of Canadians, reaching >70% in those with diabetes and obesity. Many progress from reversible stages of liver fat accumulation to inflammation (non-alcoholic steatohepatitis-NASH) and fibrosis; t
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Canada Research Chairs - Tier 1
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批准号:424778
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项目类别:
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资助金额:$101.99万
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财政年份:2019
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负责人:Gaisano Herbert Y
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依托单位:
Novel excitosomes mediating exocytosis in neuroendocrine cells
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批准号:379534
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项目类别:Operating Grants
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资助金额:$63.53万
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财政年份:2018
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负责人:Gaisano Herbert Y
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依托单位:
Role of autophagy dysregulation in pancreatitis caused by alcohol and glucagon-like peptide
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批准号:379648
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项目类别:Operating Grants
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资助金额:$64.93万
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财政年份:2018
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负责人:Gaisano Herbert Y
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依托单位:
alpha-cell glucagon secretion: regulated exocytosis, dysregulation & rescue of type-1 diabetes
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批准号:341268
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项目类别:Operating Grants
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资助金额:$57.09万
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财政年份:2016
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负责人:Gaisano Herbert Y
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依托单位:
Rescuing the insulin exocytotic defects in type 2 diabetes
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批准号:266220
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项目类别:Operating Grants
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资助金额:$50.99万
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财政年份:2012
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负责人:Gaisano Herbert Y
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依托单位:
Mechanisms of pancreatitis elucidated on human pancreas in situ
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批准号:237847
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项目类别:Operating Grants
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资助金额:$55.58万
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财政年份:2011
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负责人:Gaisano Herbert Y
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依托单位:
SNARE regulation of potassium channels in neuroendocrine cells
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批准号:181058
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项目类别:Operating Grants
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资助金额:$50.9万
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财政年份:2009
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负责人:Gaisano Herbert Y
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依托单位:
海外基金