Novel excitosomes mediating exocytosis in neuroendocrine cells
Novel excitosomes mediating exocytosis in neuroendocrine cells
批准号:
379534
负责人:
Gaisano Herbert Y
金额:
$63.53万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-03-01 至 2023-03-01
中文摘要
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英文摘要
Pancreatic beta cells secrete insulin in biphasic manner, an initial peak phase (~15 min) followed by a sustained phase (several hours), to ensure continuous assimilation of circulating nutrients into tissues. In type-2 diabetes, both phases are perturbed
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