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Novel excitosomes mediating exocytosis in neuroendocrine cells

Novel excitosomes mediating exocytosis in neuroendocrine cells
介导神经内分泌细胞胞吐作用的新型兴奋体
批准号:
379534
负责人:
Gaisano Herbert Y
金额:
$63.53万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-03-01 至 2023-03-01

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中文摘要
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英文摘要
Pancreatic beta cells secrete insulin in biphasic manner, an initial peak phase (~15 min) followed by a sustained phase (several hours), to ensure continuous assimilation of circulating nutrients into tissues. In type-2 diabetes, both phases are perturbed
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Stage-specific treatment of human non-alcoholic fatty liver disease: elucidating the precise mechanisms of actions of glucagon-like peptide-1 receptor agonists and novel anti-fibrosis molecules
  • 批准号:
    468757
  • 项目类别:
    Operating Grants
  • 资助金额:
    $81.37万
  • 财政年份:
    2022
  • 负责人:
    Gaisano Herbert Y
  • 依托单位:
Canada Research Chairs - Tier 1
  • 批准号:
    424778
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2019
  • 负责人:
    Gaisano Herbert Y
  • 依托单位:
Role of autophagy dysregulation in pancreatitis caused by alcohol and glucagon-like peptide
  • 批准号:
    379648
  • 项目类别:
    Operating Grants
  • 资助金额:
    $64.93万
  • 财政年份:
    2018
  • 负责人:
    Gaisano Herbert Y
  • 依托单位:
alpha-cell glucagon secretion: regulated exocytosis, dysregulation & rescue of type-1 diabetes
  • 批准号:
    341268
  • 项目类别:
    Operating Grants
  • 资助金额:
    $57.09万
  • 财政年份:
    2016
  • 负责人:
    Gaisano Herbert Y
  • 依托单位:
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