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Rescuing the insulin exocytotic defects in type 2 diabetes

Rescuing the insulin exocytotic defects in type 2 diabetes
挽救 2 型糖尿病的胰岛素胞吐缺陷
批准号:
266220
负责人:
Gaisano Herbert Y
金额:
$50.99万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-09-01 至 2017-09-01

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中文摘要
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英文摘要
In pancreatic islet beta-cells, only a small number of insulin secretory granules (SGs) are docked onto the plasma membrane (PM) and only a fraction of these docked SGs are competent or 'primed' for immediate release. Each of these sequential steps leadin
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会议论文
Stage-specific treatment of human non-alcoholic fatty liver disease: elucidating the precise mechanisms of actions of glucagon-like peptide-1 receptor agonists and novel anti-fibrosis molecules
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    468757
  • 项目类别:
    Operating Grants
  • 资助金额:
    $81.37万
  • 财政年份:
    2022
  • 负责人:
    Gaisano Herbert Y
  • 依托单位:
Canada Research Chairs - Tier 1
  • 批准号:
    424778
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2019
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    Gaisano Herbert Y
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Novel excitosomes mediating exocytosis in neuroendocrine cells
  • 批准号:
    379534
  • 项目类别:
    Operating Grants
  • 资助金额:
    $63.53万
  • 财政年份:
    2018
  • 负责人:
    Gaisano Herbert Y
  • 依托单位:
Role of autophagy dysregulation in pancreatitis caused by alcohol and glucagon-like peptide
  • 批准号:
    379648
  • 项目类别:
    Operating Grants
  • 资助金额:
    $64.93万
  • 财政年份:
    2018
  • 负责人:
    Gaisano Herbert Y
  • 依托单位:
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