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A novel oncolytic virotherapy to overcome drug-resistance in acute myeloid leukemia

A novel oncolytic virotherapy to overcome drug-resistance in acute myeloid leukemia
一种克服急性髓系白血病耐药性的新型溶瘤病毒疗法
批准号:
477256
负责人:
Jiang Xiaoyan
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-10-01 至 2023-10-01

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中文摘要
翻译
血癌(白血病)是一种影响血液和骨髓的癌症;当骨髓中产生的血细胞生长失控时,就会发生这种疾病。 特别是,急性髓性白血病(AML)是最常见的人类白血病,
英文摘要
Blood cancer (leukemia) is a type of cancer that affects the blood and bone marrow; the disease develops when blood cells produced in the bone marrow grow out of control. In particular, acute myeloid leukemia (AML) is the most common human leukemia and i
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Targeting a novel miR-185/PAK6 axis to overcome drug-resistance in human leukemia
  • 批准号:
    409434
  • 项目类别:
    Operating Grants
  • 资助金额:
    $65.76万
  • 财政年份:
    2019
  • 负责人:
    Jiang Xiaoyan
  • 依托单位:
Targeting Key Autophagy Proteins/Pathways for Treatment of Human Leukemia
  • 批准号:
    368208
  • 项目类别:
    Operating Grants
  • 资助金额:
    $57.4万
  • 财政年份:
    2017
  • 负责人:
    Jiang Xiaoyan
  • 依托单位:
Targeting Drug-Insensitive CML Stem Cells with Combination Therapy of New ABL and PP2A Inhibitors
  • 批准号:
    291592
  • 项目类别:
    Operating Grants
  • 资助金额:
    $47.99万
  • 财政年份:
    2013
  • 负责人:
    Jiang Xiaoyan
  • 依托单位:
Molecular Targeting of Critical Domains of AHI-1 Oncoprotein in Chronic Myeloid Leukemia Stem Cells Resistant to Current Tyrosine Kinase Inhibitor Therapy
  • 批准号:
    238855
  • 项目类别:
    Operating Grants
  • 资助金额:
    $46.39万
  • 财政年份:
    2011
  • 负责人:
    Jiang Xiaoyan
  • 依托单位:
海外基金