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Targeting a novel miR-185/PAK6 axis to overcome drug-resistance in human leukemia

Targeting a novel miR-185/PAK6 axis to overcome drug-resistance in human leukemia
靶向新型 miR-185/PAK6 轴以克服人类白血病的耐药性
批准号:
409434
负责人:
Jiang Xiaoyan
金额:
$65.76万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2024-09-01

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中文摘要
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英文摘要
Blood cancer (leukemia) is common, with ~55,000 new cases expected in the United States and Canada in 2019. The National Cancer Institute (US) calculated an overall 5-year survival rate of 56% for various blood cancers. This is because drug resistance and
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A novel oncolytic virotherapy to overcome drug-resistance in acute myeloid leukemia
  • 批准号:
    477256
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Jiang Xiaoyan
  • 依托单位:
Targeting Key Autophagy Proteins/Pathways for Treatment of Human Leukemia
  • 批准号:
    368208
  • 项目类别:
    Operating Grants
  • 资助金额:
    $57.4万
  • 财政年份:
    2017
  • 负责人:
    Jiang Xiaoyan
  • 依托单位:
Targeting Drug-Insensitive CML Stem Cells with Combination Therapy of New ABL and PP2A Inhibitors
  • 批准号:
    291592
  • 项目类别:
    Operating Grants
  • 资助金额:
    $47.99万
  • 财政年份:
    2013
  • 负责人:
    Jiang Xiaoyan
  • 依托单位:
Molecular Targeting of Critical Domains of AHI-1 Oncoprotein in Chronic Myeloid Leukemia Stem Cells Resistant to Current Tyrosine Kinase Inhibitor Therapy
  • 批准号:
    238855
  • 项目类别:
    Operating Grants
  • 资助金额:
    $46.39万
  • 财政年份:
    2011
  • 负责人:
    Jiang Xiaoyan
  • 依托单位:
海外基金