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Targeting Drug-Insensitive CML Stem Cells with Combination Therapy of New ABL and PP2A Inhibitors

Targeting Drug-Insensitive CML Stem Cells with Combination Therapy of New ABL and PP2A Inhibitors
使用新型 ABL 和 PP2A 抑制剂联合治疗靶向药物不敏感的 CML 干细胞
批准号:
291592
负责人:
Jiang Xiaoyan
金额:
$47.99万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-09-01 至 2018-09-01

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中文摘要
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英文摘要
Leukemia is a common blood cancer, with about 44,600 and 4,900 new cases expected to be diagnosed in the United States and Canada respectively in 2013. The introduction of Imatinib medication has improved treatment of chronic myeloid leukemia (CML), but e
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A novel oncolytic virotherapy to overcome drug-resistance in acute myeloid leukemia
  • 批准号:
    477256
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  • 资助金额:
    $7.29万
  • 财政年份:
    2022
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Targeting a novel miR-185/PAK6 axis to overcome drug-resistance in human leukemia
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    409434
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    2019
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Targeting Key Autophagy Proteins/Pathways for Treatment of Human Leukemia
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    368208
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    Operating Grants
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    $57.4万
  • 财政年份:
    2017
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Molecular Targeting of Critical Domains of AHI-1 Oncoprotein in Chronic Myeloid Leukemia Stem Cells Resistant to Current Tyrosine Kinase Inhibitor Therapy
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    238855
  • 项目类别:
    Operating Grants
  • 资助金额:
    $46.39万
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  • 负责人:
    Jiang Xiaoyan
  • 依托单位:
海外基金