Urgent and Cost-Effective Robot-Controlled Nuclear Quadrupole Resonance Spectrometer

紧急且具有成本效益的机器人控制核四极共振谱仪

• 批准号: RTI-2023-00015
• 负责人: Bryce, David
• 金额: $ 10.93万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=748187
• 关键词: Urgent; Cost; Effective; Robot; Controlled

We present a cost-effective solution to an urgent unmet need for a robot-controlled nuclear quadrupole resonance (NQR) spectrometer console and associated amplifiers and probe. There are no such spectrometers available in Canada to our knowledge, and costly resources are being consumed by using a temporary work-around reliant on access to NMR spectrometers. A significant issue arises in studying many of the elements of the periodic table by nuclear magnetic resonance (NMR) spectroscopy. 75% of the elements in the periodic table are quadrupolar (nuclear spin I >1/2), resulting oftentimes in substantial spectral broadening. In the case of isotopes such as germanium-73, iodine-127, and antimony-121, for example, quadrupolar broadening is so severe that solid-state NMR becomes impractical and intractable, even in the highest commercially available magnetic fields. NQR spectroscopy, carried out in the absence of an external applied magnetic field, becomes the only option. The requested equipment will allow us to overcome the limitations imposed by quadrupolar broadening observed in solid-state NMR spectroscopy, and truly open the complete periodic table of elements and isotopes for study. We will also develop in-situ mechanochemistry tools for NQR. The auto-tuning functionality, coupled with advanced radiofrequency pulse sequences, will greatly accelerate and advance multiples lines of our academic and industrial research. Approximately 20/year highly qualified personnel (HQP) supervised directly by the co-applicants will immediately benefit from access to this instrument. Further indirect training benefits will be realized through extensive ongoing and future collaborative work. As part of the NMR Core Facility there are > 200 other potential HQP users. Adding NQR spectroscopy to their arsenal of NMR and solid-state chemistry skills will help make them highly sought-after candidates for employment in the academic, industrial, and government sectors.

我们提出了一种经济有效的解决方案，以满足对机器人控制的核四极共振(NQR)光谱仪控制台和相关放大器和探头的迫切需求。据我们所知，加拿大没有这样的光谱仪，使用依赖于访问核磁共振光谱仪的临时解决办法正在消耗昂贵的资源。在用核磁共振光谱学研究元素周期表的许多元素时，出现了一个重要问题。元素周期表中75%的元素是四极元素(核自旋i&gt；1/2)，这往往导致光谱的显著展宽。例如，对于Ge-73、I-127和Sb-121等同位素，四极展宽是如此严重，以至于固态核磁共振变得不切实际和难以处理，即使在商业上可用的最高磁场中也是如此。在没有外加磁场的情况下进行的NQR光谱分析成为唯一的选择。所要求的设备将使我们能够克服在固态核磁共振光谱中观察到的四极展宽带来的限制，并真正打开完整的元素和同位素元素周期表以供研究。我们还将为NQR开发原位机械力化学工具。自动调谐功能与先进的射频脉冲序列相结合，将极大地加速和推进我们的学术和工业研究的多条线路。由共同申请者直接监督的每年约20名高素质人员(HQP)将立即受益于获得这一文书。将通过广泛的、持续的和未来的协作工作实现进一步的间接培训效益。作为核磁共振核心设施的一部分，还有&gt；200其他潜在的HQP用户。将NQR光谱学添加到他们的核磁共振和固态化学技能库中，将有助于使他们成为学术、工业和政府部门就业的热门人选。